IL-6 is a central mediator of the immediate induction of hepatic acute phase proteins (APP) in the liver during infection and after injury. but increased IL-6 activity has been associated with multiple pathological conditions. In hepatocytes. IL-6 activates JAK1-STAT3 signaling that induces the negative feedback regulator SOCS3 and expression of APPs. https://quarterfoures.shop/product-category/mens/